Denaturing Gradient Gel Electrophoresis Unit
Our denaturing gradient gel electrophoresis (DGGE) Unit is a specialized laboratory apparatus employed in molecular biology and genomics research for the separation and analysis of DNA fragments based on their sequence variations. It utilizes a polyacrylamide gel with a linear or gradient denaturant, typically formamide and urea, to induce DNA denaturation. As DNA fragments migrate through the gel under the influence of an electric field, they experience different levels of denaturation, leading to distinct migration patterns. DGGE Units are integral for applications such as genetic fingerprinting, mutation analysis, and ecological studies, providing valuable insights into DNA sequence variations and their functional implications.